The river Nile has been subjected to different sources of pollution that have an effect on its biological characteristics as industrial, agricultural, and municipal wastes 123456. Organochlorine pesticides are washed into the aquatic system by water runoff and eroding.

Pesticides may drift throughout application and contaminate aquatic systems samples 7. Organochlorine pesticides (OCPs) like hexa-chlorocyclohexane (HCH), dichloro-diphenyl and endosulfan are among the foremost wide applied chemicals within the world 8, Organophosphate  (O, O -diethyl O -(3,5,6-trichloro-2-pyridinyl) phosphorothioate; CAS No. 2921-88-2; CPY) 9.

The river Nile influences the public health, social life 10.Treated domestic waste material is being reused for irrigation with 1112. Industrial waste products are the second of the most sources of river pollution due to the toxicant chemicals and organic loading 13. All major pollution sources deteriorate river water. Indication of these pollutants has been reportable by microbiological quality measurements on several sections of the stream river 1413. Sixteen organochlorine pesticides were detected within the drains and to less degree in canals 15. The environmental pollution has a direct and indirect impact on natural resources, human activities 161718.The unregulated application of pesticides will cause adverse effects to human health and to the ecosystems 19, 23456.

Chlorinated pesticides (OCPs) and polychlorinated biphenyls (PCBs) were habitually utilized in agricultural and industrial functions 20. PCBs will still be unintentional byproducts, through the combustion of wastes and different industrial processes 21. The World Health Organization (WHO) has declared that organochlorines are found to be malignant neoplastic disease compounds in animal models 22.

From the cited table it was found that; the analysis of fish muscles in summer season, 2017 showed a high level of organic pollutants in both the polluted site and the reference site with a high significance in the polluted site. The organic pollutant that are reported in the muscle of fish in the polluted site were reported as; Dimethomorph-(E), Hexestrol, Diisobutyl phthalate, Diamyl phthalate, Vamidothion,

Di-n-butylphthalate, Diamyl phthalate, Di-n-propyl phthalate, Chlorpyrifos, Phorate sulfoxide, Exaltolide 15, Chlorfenapyr, Pyridate, Ethofumesate, Bis(2-ethylhexyl)phthalate, Dicyclohexyl phthalate, Di-n-octyl phthalate, Tricresylphosphate, meta-, XMC (3,4-Dimethylphenyl N-methyl, XMC (3,5-Dimethylphenyl N-methyl, Hexestrol, Thymol, Kinoprene, Diisobutyl phthalate, Diisobutyl phthalate, Di-n-hexyl phthalate, Di-n-hexyl phthalate, Carbofuran-3-keto,

Tefluthrin, cis-, Carbofuran-7-phenol, Carbofuran, Dicyclohexyl phthalate, Di-n-propyl phthalate, Di-n-propyl phthalate, Bis(2-ethylhexyl)phthalate, Ethofumesate, Hexestrol, Kinoprene, Di-n-hexyl phthalate, Exaltolide 15, Spiroxamine metabolite (4-tert-b), Chlorfenapyr, Tricresylphosphate, para, Tricresylphosphate, meta-, Tricresylphosphate, ortho-, XMC (3,5-Dimethylphenyl N-methyl, XMC (3,4-Dimethylphenyl N-methyl, Fluroxypyr-1-methylheptyl ester, Cashmeran, Propargite metabolite ^Cyclohexa., and Quinoclamine. Table 1.

From the above cited table; results showed that Diisobutyl phthalate, Bis(2-ethylhexyl)phthalate, Pyridate and Ethofumesate were detected in winter season organic pollutant in the polluted site, whereas, Bis (2-ethylhexyl)phthalate, and Pyridate were the only organic pollutants that were found in winter in the reference site. The authors recommend that fishing in winter is better than that of summer and that fishing from the reference site is preferred. Table 2 and Table 3.

From the above cited table it is concluded that; the order of the % of organing pollutants which were found in summer in the muscle of fish collected from the polluted site followed the order of: Chlorpyrifos> Diamyl phthalate> Diisobutylphthalate> Di-n-butylphthalate> Diamyl phthalate> Bis(2-ethylhexyl)phthalate, whereas in the reference site in summer, it was Chlorpyrifos> Chlorfenapyr> Di-n-butylphthalate> Diisobutylphthalate> Hexestrol> Di-nhexyl phthalate. The accumulation patterns of organic pollutants in the polluted site in winter in the muscles of O. niloticus, were in the following order: Bis(2-ethylhexyl)phthalate> Pyridate> Ethofumesate, whereas in the reference site it was; Bis(2-ethylhexyl)phthalate> Pyridate.

The present study had been undertaken so as to screen the pollutants content in fish muscles collected from EL-Mahmodia stream, El-Beheira Governorate. Egypt is that the second largest producer of Tilapia, that thought-about the foremost common fish presently being, refined commercially 2324. GC–MS analysis of fish muscles collected from EL-Mahmodia stream water showed the presence of organic chemicals, fungicide, fatty acids and carboxyl acids. Most of the organic pollutants detected at the peaks in GC–MS knowledge analysis were known as endocrine disrupting phthalate esters, fatty acids, phenolic resin acids, carcinogens, and aquatic toxicants 25. Phthalates like acid, chemical group tetradecyl organic compound, acid, octadecyl organic compound acid, chemical group 2-ethylbutyl organic compound, acid, di(2-propylpentyl) are discharged together with industrial wastewaters cause pollution and disturb the ecology of the receiving water bodies by making serious toxicity to aquatic organisms as results of bioaccumulation and therefore cause unhealthful, genotoxic effects also as disturb the inhibitor defense system 262728, 456. Phthalates are reportable to cause endocrine disruption in humans and animals upon long run exposure 2925.

 The standard of river water worsened greatly within the past few years 12. The main pollution sources of river and main canals are effluents from agricultural drains and treated or part treated industrial and municipal waste waters, as well as oil like monounsaturated fatty acid and wastes from traveler and watercourse boats 30234316. The water contains dissolved salts that washed from agricultural lands also as residues of pesticides and fertilizers, at the tip these pesticides collected in EL-Mahmodia stream water 1223456. In El-Mahmodia stream there is quantity of organochlorine pesticides detected within the stream water samples like Dieldrin 32, As DDD detected in stream water samples. These elevated values are beyond natural occurring and at some spots of river are higher than allowable limits for healthy water streams 3323456. Pollution of the aquatic surroundings by inorganic and organic chemicals may be a major issue movement a heavy threat to the survival of aquatic organisms 34.

The aquatic surroundings is subjected to varied varieties of pollutants that enter water bodies this can be a results of human activities that are associated with industrial, domestic and agricultural wastes that are drop into water bodies 1623456. Industrial waste water is taken into account as the most sources of river pollution owing to the unhealthful chemicals and organic loading during this waste water 3523456. The quantities and quality of effluent from agricultural lands are extremely variable. It contains animal wastes, plant nutrients 36. The persistence of the organochlorine compounds and their metabolites, that are typically that are typically additional unhealthful  3738.

Azab et al.39 reported that in summer season, organochlorines were considerably higher in water samples. The results of this study are in agreement there with of Azab et al.39 as there was a high important totally different of organic pollutants within the muscles of fish that were collected in summer quite that were collected in winter.

The authors extremely suggest eating fish that were collected from El-Mahodia stream in winter quite that in summer as they are less polluted. Bioaccumulation of such compounds causes mutagenic effects to humans, animals, and aquatic organisms 404142262728. The 2, 6-dihydroxybenzoic acids, those were detected within the water samples, are the key metabolites of the polyaromatic hydrocarbons throughout effluent treatment 43442945.

In EL-Behira Governorate, pesticides are used along a large scale; organochlorine and organophosphate are persistent pesticides which leave residues in drinking water that remain for days to many years. Organophosphates are found in high rate in the stream, Chloropyrifos as an Organophosphates pesticides was found in the stream water. The current study revealed that the water quality of El-Mahmodia canal is contaminated with elevated levels of organic pollutants: pesticides, plasticizers, plant residues compared to standard safety permissible guidelines.