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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JAN</journal-id>
      <journal-title-group>
        <journal-title>Journal of Advances in Nanotechnology</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2689-2855</issn>
      <publisher>
        <publisher-name>Open Access Pub</publisher-name>
        <publisher-loc>United States</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.14302/issn.2689-2855.jan-19-3012</article-id>
      <article-id pub-id-type="publisher-id">JAN-19-3012</article-id>
      <article-categories>
        <subj-group>
          <subject>in-brief</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Quantum Dots- Tiny Semiconductor Nanodots</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Nida</surname>
            <given-names>Tabassum Khan</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842211804">1</xref>
          <xref ref-type="aff" rid="idm1842231292">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Muhammad</surname>
            <given-names>Jibran Khan</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842211804">1</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842211804">
        <label>1</label>
        <addr-line>Department of Biotechnology, Faculty of Life Sciences and Informatics, Balochistan University of Information Technology Engineering and Management Sciences, (BUITEMS), Quetta, Pakistan</addr-line>
      </aff>
      <aff id="idm1842231292">
        <label>*</label>
        <addr-line>corresponding author</addr-line>
      </aff>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Muhammad</surname>
            <given-names>Humayun</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842077700">1</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842077700">
        <label>1</label>
        <addr-line>Huazhong University of Science and Technology, China.</addr-line>
      </aff>
      <author-notes>
        <corresp>
  Nida Tabassum Khan, <addr-line>Department of Biotechnology, Faculty of Life Sciences and                      Informatics, </addr-line><addr-line>Balochistan</addr-line><addr-line> University of Information Technology Engineering and Management Sciences, (BUITEMS), Quetta,  Pakistan</addr-line>, Email: <email>nidatabassumkhan@yahoo.com</email></corresp>
        <fn fn-type="conflict" id="idm1842987004">
          <p>The authors have declared that no competing interests exist.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub" iso-8601-date="2019-09-19">
        <day>19</day>
        <month>09</month>
        <year>2019</year>
      </pub-date>
      <volume>1</volume>
      <issue>2</issue>
      <fpage>1</fpage>
      <lpage>4</lpage>
      <history>
        <date date-type="received">
          <day>04</day>
          <month>09</month>
          <year>2019</year>
        </date>
        <date date-type="accepted">
          <day>18</day>
          <month>09</month>
          <year>2019</year>
        </date>
        <date date-type="online">
          <day>19</day>
          <month>09</month>
          <year>2019</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© </copyright-statement>
        <copyright-year>2019</copyright-year>
        <copyright-holder>Nida Tabassum Khan, et al.</copyright-holder>
        <license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="http://openaccesspub.org//jan/article/1166">This article is available from http://openaccesspub.org//jan/article/1166</self-uri>
      <abstract>
        <p>Quantum dots can be defined as semiconductor nanostructures which are artificial in nature and ranges from 2-10 nm in size. These tiny nanocrystals become excited under illumination and emits colors of different wavelength. Quantum dots possess unique properties determined by their structure (hollow or solid), size, shape and composition. Fabrication of Quantum dots is achieved by several methods such as electron beam lithography, epitaxy or by means of colloidal synthesis.</p>
      </abstract>
      <kwd-group>
        <kwd>DNA assays</kwd>
        <kwd>Crystalline lattice structures</kwd>
        <kwd>Luminescence</kwd>
        <kwd>Photo-bleaching</kwd>
        <kwd>Semi-conducting nanoparticles.</kwd>
      </kwd-group>
      <counts>
        <fig-count count="0"/>
        <table-count count="1"/>
        <page-count count="4"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <sec id="idm1842083532" sec-type="intro">
      <title>Introduction</title>
      <p>The word ‘Quantum’ itself is derived from a Latin word meaning ‘amount’ and can be defined as small unit of physical property like energy or                 matter <xref ref-type="bibr" rid="ridm1841982492">1</xref>. In 1900 physicist Max Planck discovered that like matter radiation existed in discrete units of energy, hence named these units as “quanta” <xref ref-type="bibr" rid="ridm1841984004">2</xref>. Similarly, quantum dots can be defined as semiconductor nanostructures which are artificial in nature and ranges from 2-10 nm in size <xref ref-type="bibr" rid="ridm1841996508">3</xref><xref ref-type="bibr" rid="ridm1842093508">4</xref>.These tiny nanocrystals become excited under illumination and emits colors of different wavelength <xref ref-type="bibr" rid="ridm1841839140">5</xref>. Quantum dots possess unique properties determined by their structure (hollow or solid), size, shape and composition <xref ref-type="bibr" rid="ridm1841844540">6</xref>.Sometimes these are also referred as artificial atoms <xref ref-type="bibr" rid="ridm1841842236">7</xref>.  Quantum dots have different crystalline lattice structures so when pressure is applied they form very thin semiconductor films <xref ref-type="bibr" rid="ridm1841827884">8</xref>. As a result, the flat film later due to stress tends to separate into dots in three dimensions <xref ref-type="bibr" rid="ridm1841832492">9</xref>. </p>
      <p>Physiochemical Properties of Quantum dots is mentioned in <xref ref-type="table" rid="idm1843158484">Table 1</xref>.</p>
      <table-wrap id="idm1843158484">
        <label>Table 1.</label>
        <caption>
          <title> Physiochemical Properties of Quantum dots</title>
        </caption>
        <table rules="all" frame="box">
          <tbody>
            <tr>
              <td>S.no</td>
              <td>Physiochemical Properties</td>
              <td> </td>
            </tr>
            <tr>
              <td>1</td>
              <td>Size</td>
              <td>Microscopic, 2-10nm (10-50 atoms) <xref ref-type="bibr" rid="ridm1841882572">10</xref></td>
            </tr>
            <tr>
              <td>2</td>
              <td>Configuration</td>
              <td>Confined in three-dimensions <xref ref-type="bibr" rid="ridm1841881924">11</xref></td>
            </tr>
            <tr>
              <td>3</td>
              <td>Highly tunable</td>
              <td>Variable core sizes make them give off different colors by tuning/changing the characteristic wavelength of emitted light <xref ref-type="bibr" rid="ridm1841798220">12</xref>.</td>
            </tr>
            <tr>
              <td>4</td>
              <td>Excitable</td>
              <td>Can excite to higher energy level to emit light of respective                    wavelength <xref ref-type="bibr" rid="ridm1841795052">13</xref></td>
            </tr>
            <tr>
              <td>5</td>
              <td>Shapes</td>
              <td>Various including cubes, spheres and pyramids <xref ref-type="bibr" rid="ridm1841790372">14</xref></td>
            </tr>
            <tr>
              <td>6</td>
              <td>Resistance</td>
              <td>Resistance to photo-bleaching, photo-degradation and                         chemical- degradation <xref ref-type="bibr" rid="ridm1841786700">15</xref><xref ref-type="bibr" rid="ridm1841772460">16</xref>.</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <sec id="idm1842039756">
        <title>Types of Quantum Dots </title>
        <p>There are 3 types of Quantum dots on the basis of their composition and structure <xref ref-type="bibr" rid="ridm1841770732">17</xref>.</p>
        <sec id="idm1842039612">
          <title>Core-Typed Quantum Dots</title>
          <p>Quantum dots that have internally uniform structures which is composed of a single material <xref ref-type="bibr" rid="ridm1841768860">18</xref>. They have variable electro/photo luminescence e.g. Metal chalcogenides <xref ref-type="bibr" rid="ridm1841778364">19</xref>.</p>
        </sec>
        <sec id="idm1842040692">
          <title>Core-shell Quantum Dots</title>
          <p>Also known as Core-Shell semi-conducting nanoparticles having variable photophysical properties e.g ZnS<xref ref-type="bibr" rid="ridm1841773684">20</xref></p>
        </sec>
        <sec id="idm1842040548">
          <title>Alloyed Quantum Dots</title>
          <p>Multicomponent semiconductor nanoparticles e.g. CdS-Se/ZnS <xref ref-type="bibr" rid="ridm1841746964">21</xref></p>
        </sec>
        <sec id="idm1842037668">
          <title>Fabrication of Quantum Dots</title>
          <p>There are 3 main approaches through which quantum dots can be prepared</p>
          <p>1. Electron beam lithography <xref ref-type="bibr" rid="ridm1841745668">22</xref></p>
          <p>2. Colloidal synthesis <xref ref-type="bibr" rid="ridm1841739764">23</xref></p>
          <p>3. Epitaxy such as Vapor Phase epitaxy, liquid phase epitaxy,molecular beam epitaxy etc <xref ref-type="bibr" rid="ridm1841739044">24</xref><xref ref-type="bibr" rid="ridm1841718932">25</xref></p>
        </sec>
      </sec>
      <sec id="idm1842031180">
        <title>Applications of Quantum Dots </title>
        <p>Used in Solar cells and photo-voltaic e.g. Graphene quantum dots <xref ref-type="bibr" rid="ridm1841712236">26</xref>.</p>
        <p>Used as fluorophores which helps in bio-sensing and bio-tagging <xref ref-type="bibr" rid="ridm1841711732">27</xref>.</p>
        <p>Used as a catalyst to form hydrocarbons <xref ref-type="bibr" rid="ridm1841723396">28</xref></p>
        <p>Luminescent quantum dots (LQD) are used in high quality displays and lighting systems <xref ref-type="bibr" rid="ridm1841719940">29</xref></p>
        <p>Quantum computing uses quantum computer that store information in quantum bits <xref ref-type="bibr" rid="ridm1841695652">30</xref>. </p>
        <p>Magnetic quantum particles are used in memory chips <xref ref-type="bibr" rid="ridm1841691692">31</xref></p>
        <p>Used in communication devices like lasers <xref ref-type="bibr" rid="ridm1841689028">32</xref>.</p>
        <p>Have biological applications including in vivo and invitro imaging, DNA assays and microarrays,labelling tumors , diagnosis /treatment of cancer , drug delivery <xref ref-type="bibr" rid="ridm1841685212">33</xref><xref ref-type="bibr" rid="ridm1841683196">34</xref><xref ref-type="bibr" rid="ridm1841678948">35</xref><xref ref-type="bibr" rid="ridm1841674340">36</xref></p>
        <p>Quantum dots have many exceeding rewards, but they do have drawbacks like they are costly, toxic, may cause environmental pollution etc <xref ref-type="bibr" rid="ridm1841703716">37</xref>. </p>
      </sec>
    </sec>
    <sec id="idm1842029596" sec-type="conclusions">
      <title>Conclusion</title>
      <p>Due to their excellent intrinsic and extrinsic properties, Quantum dots continues to amaze researchers with their immense applications.</p>
    </sec>
  </body>
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